Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...

The breakthrough came from experiments using nanopores, tiny holes only wide enough to fit a single DNA strand. Researchers ...

The technique uses a long strand of DNA with a set sequence—the template—and a bunch of shorter, premade DNA molecules that can base pair with specific spots on the template—the bricks.

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix ...

They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...

Lead author of "Distinct regulation of ATM signaling by DNA single-strand breaks and APE1," Haichao Zhao offered that the research may support future clinical trials – both for attacking cancer ...